Title : Targeting the Shc-EGFR interaction with indomethacin inhibits MAP kinase pathway signalling.

Pub. Date : 2019 Aug 10

PMID : 31100409






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Activated RTK recruits Shc, via its phosphotyrosine binding (PTB) domain (ShcPTB), precipitating the release of Erk to engage in a signalling response. Phosphotyrosine ret proto-oncogene Homo sapiens