Pub. Date : 2019 Jun
PMID : 31095448
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, the results demonstrated that capsaicin induced the activation of adenosine 5"-monophosphate-activated protein kinase (AMPK), p53 and C-jun N-terminal kinase (JNK). | Capsaicin | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | In addition, the results demonstrated that capsaicin induced the activation of adenosine 5"-monophosphate-activated protein kinase (AMPK), p53 and C-jun N-terminal kinase (JNK). | Capsaicin | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | Taken together, the present study suggests that capsaicin effectively causes cell death in human osteosarcoma MG63 cells via the activation of TRPV1-dependent (mitochondrial dysfunction, and overproduction of ROS and JNK) and TRPV1-independent (AMPK-p53) pathways. | Capsaicin | mitogen-activated protein kinase 8 | Homo sapiens |