Title : DFMO and 5-Azacytidine Increase M1 Macrophages in the Tumor Microenvironment of Murine Ovarian Cancer.

Pub. Date : 2019 Jul 1

PMID : 31088836






1 Functional Relationships(s)
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1 We tested this hypothesis in an immunocompetent mouse model for ovarian cancer and found that in vivo, 5AZA-C and DFMO, either alone or in combination, significantly increased survival, decreased tumor burden, and caused recruitment of activated (IFNgamma+) CD4+ T cells, CD8+ T cells, and NK cells. Eflornithine CD4 antigen Mus musculus