Pub. Date : 2019 May 10
PMID : 31083310
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | LPS upregulated gene expressions of NF-kappaB subunits and of ICAM-1, TNF-alpha, iNOS, and COX-2 within 8 h, which could be decreased by 18beta glycyrrhetinic acid, isoliquiritigenin and ursolic acid similarly to the anti-inflammatory drug dexamethasone. | Glycyrrhetinic Acid | tumor necrosis factor | Mus musculus |
2 | Conclusions: 18beta glycyrrhetinic acid, isoliquiritigenin, and ursolic acid inhibited the gene expressions of ICAM-1, TNF-alpha, COX-2, and iNOS, partly through inhibiting NF-kappaB expression and attenuating NF-kappaB nuclear translocation. | Glycyrrhetinic Acid | tumor necrosis factor | Mus musculus |