Title : Focused ultrasound-induced blood brain-barrier opening enhanced vascular permeability for GDNF delivery in Huntington's disease mouse model.

Pub. Date : 2019 Sep - Oct

PMID : 31079989






1 Functional Relationships(s)
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1 Reflecting the improvements observed in motor function, GDNF overexpression results in significantly decreased formation of polyglutamine-expanded aggregates, reduced oxidative stress and apoptosis, promoted neurite outgrowth, and improved neuronal survival. polyglutamine glial cell line derived neurotrophic factor Mus musculus