Pub. Date : 2019 May 10
PMID : 31077207
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our results showed that 200-800 muM PA treatment reduces cell viability, induces cell apoptosis, enhances the expression of apoptosis-related genes (Caspase 3 and B-cell lymphoma-2 (BCL-2) associated X protein (BAX)), and activates the expression of ER stress marker genes (glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP)). | Palmitic Acid | DNA-damage inducible transcript 3 | Mus musculus |
| 2 | Our results showed that 200-800 muM PA treatment reduces cell viability, induces cell apoptosis, enhances the expression of apoptosis-related genes (Caspase 3 and B-cell lymphoma-2 (BCL-2) associated X protein (BAX)), and activates the expression of ER stress marker genes (glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP)). | Palmitic Acid | DNA-damage inducible transcript 3 | Mus musculus |
| 3 | Melatonin treatment (1-10 muM) suppresses 400 muM PA-induced cell viability decrease, cell apoptosis, Caspase 3 activation, and BAX, CHOP, and GRP78 expression. | Palmitic Acid | DNA-damage inducible transcript 3 | Mus musculus |