Title : Thrombin-induced transfer of arachidonic acid in human platelets is not inhibited by trifluoperazine.

Pub. Date : 1987 Apr 29

PMID : 3107560






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1 In this study, we have shown using arachidonic-labelled human platelets that the thrombin-induced activation of a transacylase reaction was not affected by concentrations of trifluoperazine (TFP) (15 micrograms/2 X 10(9) cells) which abolished the accumulation of free [3H]arachidonic acid in the presence of the cyclooxygenase/lipoxygenase inhibitor <protein-id="100129696">BW755C. arachidonic coagulation factor II, thrombin Homo sapiens