Title : The effects of recessive lethal Notch mutations of Drosophila melanogaster on flavoprotein enzyme activities whose inhibitions cause Notch-like phenocopies.

Pub. Date : 1987 Feb

PMID : 3107544






1 Functional Relationships(s)
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1 Notch phenocopies were induced by inhibitors of enzyme activities in two biochemical pathways: the de novo pyrimidine synthesis by 5-methylorotate (inhibitor of dihydroorotate dehydrogenase) and the choline shunt by amobarbital (inhibits choline dehydrogenase) and methoxyacetate (inhibits sarcosine dehydrogenase). pyrimidine Notch Drosophila melanogaster