Title : Reactive Oxygen Species-Mediated Cezanne Inactivation by Oxidation of its Catalytic Cysteine Residue in Hepatocellular Carcinoma.

Pub. Date : 2019 Sep 23

PMID : 31072419






2 Functional Relationships(s)
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1 Moreover, we found that H2O2 could activate NF-kappaB-dependent inflammatory effect through increased induction of matrix metalloproteinase 2 (MMP2), MMP9, and intercellular adhesion molecule 1 (ICAM1) expression levels. Hydrogen Peroxide nuclear factor kappa B subunit 1 Homo sapiens
2 In addition, we found that H2O2 could prolong NF-kappaB activation by suppressing the negative regulatory functions of Cezanne in HCC cells. Hydrogen Peroxide nuclear factor kappa B subunit 1 Homo sapiens