Title : AMPK activation attenuates inflammatory response to reduce ambient PM2.5-induced metabolic disorders in healthy and diabetic mice.

Pub. Date : 2019 Sep 15

PMID : 31071567






1 Functional Relationships(s)
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1 More importantly, AICAR administration led to the significant enhancement of energy metabolism, elevation of AMPK as well as the decreased IL-6 and TNF-alpha in VAT of PM2.5-exposed mice, which suggesting that AMPK activation might attenuate the inflammatory responses in VAT via the inhibition of MAPKs and NFkappaB. acadesine interleukin 6 Mus musculus