Title : Dexamethasone inhibits cytokine production in PBMC from systemic sclerosis patients.

Pub. Date : 2019 Aug

PMID : 31069604






2 Functional Relationships(s)
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1 DEX (1.000 nM) treatment in PBMC of SSc patients stimulated with anti-CD3 and anti-CD28 promoted a significant reduction in IL-2, IL-4, IL-6, IL-10, IL-17A, IFN-gamma, TNF, IL-1beta (p < 0.001 for all), and IL-17F (p = 0.023) cytokines levels. Dexamethasone interleukin 6 Homo sapiens
2 In PBMC from healthy volunteers, we observed that DEX treatment significantly reduced IL-4, IFN-gamma (p = 0.003 for both), IL-6, IL-10, IL-17A, and TNF (p = 0.002 for all) cytokines. Dexamethasone interleukin 6 Homo sapiens