Pub. Date : 2019 Aug
PMID : 31054961
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | However, the roles and regulatory mechanisms by which CsA modulates HSP expression remain largely unknown. | Cyclosporine | heat shock protein 90 beta family member 2, pseudogene | Homo sapiens |
| 2 | Suppression of ERK1/2, GSK3beta and CK2 activities attenuated CsA-induced down-regulation of HSP expression and up-regulation of HSF1 phosphorylation. | Cyclosporine | heat shock protein 90 beta family member 2, pseudogene | Homo sapiens |
| 3 | These results indicate that CsA suppresses HSP induction during heat shock by regulating the phosphorylation and nuclear translocation of HSF1. | Cyclosporine | heat shock protein 90 beta family member 2, pseudogene | Homo sapiens |