Title : Negative feedback regulation of ErbB4 tyrosine kinase activity by ERK-mediated non-canonical phosphorylation.

Pub. Date : 2019 Jun 25

PMID : 31053301






1 Functional Relationships(s)
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1 TPA as an activator of the ERK pathway markedly induced ErbB4 phosphorylation at Thr-674, the conserved common feedback site in the intracellular JM domain, which resulted in the downregulation of tyrosine autophosphorylation. Threonine mitogen-activated protein kinase 1 Homo sapiens