Title : IGF1R/IRS1 targeting has cytotoxic activity and inhibits PI3K/AKT/mTOR and MAPK signaling in acute lymphoblastic leukemia cells.

Pub. Date : 2019 Aug 1

PMID : 31042587






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 NT157 has a stronger effect on ALL cells, and thus the direct inhibition of IRS1 may be a potential therapeutic target in ALL. NT157 hyaluronan synthase 1 Homo sapiens