Pub. Date : 2019 Jun 18
PMID : 31030942
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ang-II-induced VSMC dedifferentiation, proliferation, migration, KLF4 expression, H2O2 production and the phosphorylation of AKT, ERK1/2 were all inhibited by knockdown of P22phox. | Hydrogen Peroxide | angiotensinogen | Rattus norvegicus |
| 2 | In conclusion, these results demonstrated that p22phox promotes Ang-II-induced VSMC phenotypic switch via the H2O2-ERK1/2/AKT-KLF4 signaling pathway. | Hydrogen Peroxide | angiotensinogen | Rattus norvegicus |