Title : Hsp90 Inhibitor SNX-2112 Enhances TRAIL-Induced Apoptosis of Human Cervical Cancer Cells via the ROS-Mediated JNK-p53-Autophagy-DR5 Pathway.

Pub. Date : 2019

PMID : 31019655






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Hsp90 Inhibitor SNX-2112 Enhances TRAIL-Induced Apoptosis of Human Cervical Cancer Cells via the ROS-Mediated JNK-p53-Autophagy-DR5 Pathway. Reactive Oxygen Species tumor protein p53 Homo sapiens
2 ROS scavenger NAC rescued SNX-2112/TRAIL-induced apoptosis and suppressed SNX-2112-induced p-JNK and p53. Reactive Oxygen Species tumor protein p53 Homo sapiens