Title : Molecular dynamics investigation of a redox switch in the anti-HIV protein SAMHD1.

Pub. Date : 2019 Sep

PMID : 31017331






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Active SAMHD1 tetramers are assembled by GTP-Mg+2-dNTP cross bridges and cleave the triphosphate groups of dNTPs at a K m of ~10 muM, which is consistent with dNTP concentrations in cycling cells, but far higher than the equivalent concentration in quiescent cells. triphosphoric acid latexin Homo sapiens