Pub. Date : 2019 Jun
PMID : 31003147
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recipient ABCB1, donor and recipient CYP3A5 genotypes influence tacrolimus pharmacokinetics in liver transplant cases. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | METHODS: Meta-analysis was carried out to evaluate how donor/recipient CYP3A5 (n = 678) and recipient ABCB1 (n = 318) genotypes influence tacrolimus pharmacokinetics till one-month of transplantation. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | CONCLUSIONS: The donor and recipient CYP3A5*3 polymorphism influences tacrolimus pharmacokinetics in the first month post-transplantation, whereas the association with recipient ABCB1 3435 C > T is inconclusive. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |