Pub. Date : 2019 Jun
PMID : 30990944
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Prolyl oligopeptidase regulates progesterone secretion via the ERK signaling pathway in murine luteal cells. | Progesterone | prolyl endopeptidase | Mus musculus |
| 2 | In contrast, POP overexpression increased progesterone secretion. | Progesterone | prolyl endopeptidase | Mus musculus |
| 3 | To clarify the role of ERK1/2 signaling in POP-regulated progesterone synthesis, U0126-EtOH, an inhibitor of the ERK signaling pathway, was used to treat luteal cells. | Progesterone | prolyl endopeptidase | Mus musculus |
| 4 | Overall, POP regulates progesterone secretion by stimulating the expression of CYP11A, 3beta-HSD, and StAR in luteal cells. | Progesterone | prolyl endopeptidase | Mus musculus |