Title : S-nitrosylation of the Peroxiredoxin-2 promotes S-nitrosoglutathione-mediated lung cancer cells apoptosis via AMPK-SIRT1 pathway.

Pub. Date : 2019 Apr 15

PMID : 30988280






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Peroxiredoxin-2 (Prdx2), an antioxidant enzyme, plays an important role in the protection of cancer cells from oxidative radical damage caused by hydrogen dioxide (H2O2), which is a potential target for cancer therapy. Hydrogen Peroxide peroxiredoxin 2 Homo sapiens
2 Peroxiredoxin-2 (Prdx2), an antioxidant enzyme, plays an important role in the protection of cancer cells from oxidative radical damage caused by hydrogen dioxide (H2O2), which is a potential target for cancer therapy. Hydrogen Peroxide peroxiredoxin 2 Homo sapiens
3 Peroxiredoxin-2 (Prdx2), an antioxidant enzyme, plays an important role in the protection of cancer cells from oxidative radical damage caused by hydrogen dioxide (H2O2), which is a potential target for cancer therapy. Hydrogen Peroxide peroxiredoxin 2 Homo sapiens
4 Peroxiredoxin-2 (Prdx2), an antioxidant enzyme, plays an important role in the protection of cancer cells from oxidative radical damage caused by hydrogen dioxide (H2O2), which is a potential target for cancer therapy. Hydrogen Peroxide peroxiredoxin 2 Homo sapiens
5 The nitrosylation of Prdx2 at Cys51 and Cys172 sites disrupted the formation of Prdx2 dimer and repressed the Prdx2 antioxidant activity, causing the accumulation of endogenous H2O2. Hydrogen Peroxide peroxiredoxin 2 Homo sapiens