Pub. Date : 2019 Apr 3
PMID : 30987073
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | AICAR (5-aminoimidazole-4-carbox-amide-1-beta-d-ribofuranoside), an AMP-activated protein kinase (AMPK) agonist, has demonstrated antitumor activities for several types of cancers. | acadesine | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 2 | AICAR (5-aminoimidazole-4-carbox-amide-1-beta-d-ribofuranoside), an AMP-activated protein kinase (AMPK) agonist, has demonstrated antitumor activities for several types of cancers. | acadesine | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 3 | AICAR (5-aminoimidazole-4-carbox-amide-1-beta-d-ribofuranoside), an AMP-activated protein kinase (AMPK) agonist, has demonstrated antitumor activities for several types of cancers. | acadesine | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 4 | AICAR (5-aminoimidazole-4-carbox-amide-1-beta-d-ribofuranoside), an AMP-activated protein kinase (AMPK) agonist, has demonstrated antitumor activities for several types of cancers. | acadesine | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 5 | In addition, our results demonstrated that AICAR induces apoptosis, attenuates transforming growth factor (TGF)-beta-induced cell migration, invasion and EMT-related protein expression, and enhances the chemosensitivity to docetaxel in prostate cancer cells through regulating the AMPK/mTOR-dependent pathway. | acadesine | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |