Title : Design, synthesis, evaluation and molecular modeling study of 4-N-phenylaminoquinolines for Alzheimer disease treatment.

Pub. Date : 2019 Jun 1

PMID : 30956012






1 Functional Relationships(s)
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1 Compound 11b showed significant inhibitory activities on AChE and BChE with IC50 values of 0.86 and 2.65 muM, respectively, a lot better than that of reference drug galanthamine. Galantamine acetylcholinesterase (Cartwright blood group) Homo sapiens