Title : B7-H3 promotes aerobic glycolysis and chemoresistance in colorectal cancer cells by regulating HK2.

Pub. Date : 2019 Apr 5

PMID : 30952834






1 Functional Relationships(s)
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1 Furthermore, we showed that B7-H3 increased glucose consumption and lactate production by promoting hexokinase 2 (HK2) expression in CRC cells, and we also found that HK2 was a key mediator of B7-H3-induced CRC chemoresistance. Lactic Acid hexokinase 2 Homo sapiens