Pub. Date : 2019 Apr
PMID : 30952710
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | P-Glycoprotein Overexpression Is Associated With Cisplatin Resistance in Human Osteosarcoma. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | RESULTS: P-gp expression levels were associated with cisplatin efficacy in OS patients. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | OS cells with higher P-gp expression were more resistant to cisplatin. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | Knockdown or inhibition of P-gp sensitized OS cells to cisplatin. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | CONCLUSION: Down-regulating the expression of P-gp in OS maybe a promising strategy to overcome cisplatin resistance. | Cisplatin | ATP binding cassette subfamily B member 1 | Homo sapiens |