Pub. Date : 2019 Jul 23
PMID : 30930179
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Repeated treatments with the D1 dopamine receptor agonist SKF-38393 modulate cell viability via sustained ERK-Bad-Bax activation in dopaminergic neuronal cells. | 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine | Eph receptor B1 | Rattus norvegicus |
2 | The D1 dopamine receptor agonist, SKF-38393, induces cytotoxicity in striatal dopaminergic neurons via an extracellular signal-regulated kinase (ERK) signaling cascade. | 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine | Eph receptor B1 | Rattus norvegicus |
3 | The D1 dopamine receptor agonist, SKF-38393, induces cytotoxicity in striatal dopaminergic neurons via an extracellular signal-regulated kinase (ERK) signaling cascade. | 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine | Eph receptor B1 | Rattus norvegicus |
4 | These results suggest that SKF-38393 induces neurotoxicity by activation of the sustained ERK-Bad-Bax system. | 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine | Eph receptor B1 | Rattus norvegicus |