Pub. Date : 2019
PMID : 30915355
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In addition, Ubenimex downregulates expression of membrane transport proteins, such as P-gp and MRP1, by inhibiting phosphorylation in the PI3K/AKT/mTOR pathway to increase intracellular accumulations of 5-fluorouracil and oxaliplatin, a process for which downregulation of CD13 expression is essential. | ubenimex | AKT serine/threonine kinase 1 | Homo sapiens |