Pub. Date : 2019 May
PMID : 30907511
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Notably, the Sal B induced up-expression of TAZ was blocked by U0126 (the MEK-ERK inhibitor), rather than LY294002 (the PI3K-Akt inhibitor). | salvianolic acid B | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | Moreover, Sal B increased the p-ERK/ERK ratio to regulate the TAZ expression as well as the cell differentiation. | salvianolic acid B | mitogen-activated protein kinase 1 | Homo sapiens |
| 3 | Moreover, Sal B increased the p-ERK/ERK ratio to regulate the TAZ expression as well as the cell differentiation. | salvianolic acid B | mitogen-activated protein kinase 1 | Homo sapiens |
| 4 | In summary, this study suggests for the first time that Sal B targets TAZ to facilitate osteogenesis and reduce adipogenesis by activating MEK-ERK signalling pathway, which provides evidence for Sal B to be used as a potential therapeutic agent for the management of bone diseases. | salvianolic acid B | mitogen-activated protein kinase 1 | Homo sapiens |
| 5 | In summary, this study suggests for the first time that Sal B targets TAZ to facilitate osteogenesis and reduce adipogenesis by activating MEK-ERK signalling pathway, which provides evidence for Sal B to be used as a potential therapeutic agent for the management of bone diseases. | salvianolic acid B | mitogen-activated protein kinase 1 | Homo sapiens |