Pub. Date : 2019
PMID : 30904097
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Through the discovery of the TSC1 and TSC2 genes and the signaling pathways responsible for the pathology of TSC, a new drug target called mechanistic target of rapamycin complex 1 (mTORC1) was discovered. | Sirolimus | TSC complex subunit 1 | Homo sapiens |
2 | Through the discovery of the TSC1 and TSC2 genes and the signaling pathways responsible for the pathology of TSC, a new drug target called mechanistic target of rapamycin complex 1 (mTORC1) was discovered. | Sirolimus | TSC complex subunit 1 | Homo sapiens |
3 | Rapamycin, an mTORC1 inhibitor, is now the only pharmacological therapy approved for the treatment of TSC. | Sirolimus | TSC complex subunit 1 | Homo sapiens |