Title : Finding a cure for tuberous sclerosis complex: From genetics through to targeted drug therapies.

Pub. Date : 2019

PMID : 30904097






3 Functional Relationships(s)
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Protein Name
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1 Through the discovery of the TSC1 and TSC2 genes and the signaling pathways responsible for the pathology of TSC, a new drug target called mechanistic target of rapamycin complex 1 (mTORC1) was discovered. Sirolimus TSC complex subunit 1 Homo sapiens
2 Through the discovery of the TSC1 and TSC2 genes and the signaling pathways responsible for the pathology of TSC, a new drug target called mechanistic target of rapamycin complex 1 (mTORC1) was discovered. Sirolimus TSC complex subunit 1 Homo sapiens
3 Rapamycin, an mTORC1 inhibitor, is now the only pharmacological therapy approved for the treatment of TSC. Sirolimus TSC complex subunit 1 Homo sapiens