Pub. Date : 2019 May 15
PMID : 30902848
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | By engineering a novel Gsdmd D88A knock-in mouse, we further demonstrate that this proinflammatory function of caspase-8 is counteracted by caspase-3-dependent cleavage and inactivation of GSDMD at aspartate 88, and is essential to suppress GSDMD-dependent cell lysis during caspase-8-dependent apoptosis. | Aspartic Acid | caspase 3 | Mus musculus |