Title : Enzyme kinetics of dUTPase from the planarian Dugesia ryukyuensis.

Pub. Date : 2019 Mar 22

PMID : 30902068






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Knockdown of the DUT gene in Dr, which encodes deoxyuridine 5"-triphosphate pyrophosphatase (dUTPase), promotes DNA fragmentation, inhibits regeneration, and eventually leads to death. deoxyuridine triphosphate Deoxyuridine triphosphatase Drosophila melanogaster
2 We observed the hydrolysis of dUTP by Dr-dUTPase using Cresol Red as a proton sensor. deoxyuridine triphosphate Deoxyuridine triphosphatase Drosophila melanogaster
3 The Km for dUTP was determined to be 4.0 microM, which is similar to that for human dUTPase. deoxyuridine triphosphate Deoxyuridine triphosphatase Drosophila melanogaster