Pub. Date : 2020 Feb
PMID : 30902024
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The catalytic efficiency (kcat/Km) for meperidine N-demethylation was similar between recombinant CYP2B6 and CYP2C19, but markedly lower by CYP3A4. | Nitrogen | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | These findings demonstrate that the relative CYP3A4, CYP2B6, and CYP2C19 involvement in meperidine N-demethylation depends on the enzyme activities in individual human liver microsomal samples. | Nitrogen | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |