Title : Non-nucleoside Reverse Transcriptase Inhibitors Inhibit Reverse Transcriptase through a Mutually Exclusive Interaction with Divalent Cation-dNTP Complexes.

Pub. Date : 2019 Apr 23

PMID : 30900874






1 Functional Relationships(s)
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1 Filtration assays demonstrated that divalent cation-dNTP complexes inhibited the binding of 14C-labeled EFV to RT-P/T with stronger binding complexes formed with Mn2+ inhibiting more potently than those with Mg2+. Carbon-14 MORN repeat containing 4 Homo sapiens