Pub. Date : 2019 Jul
PMID : 30898339
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Plasma copeptin levels predict disease progression and tolvaptan efficacy in autosomal dominant polycystic kidney disease. | Tolvaptan | arginine vasopressin | Homo sapiens |
| 2 | In tolvaptan-treated subjects, copeptin increased from baseline to week 3 (6.3 pmol/L versus 21.9 pmol/L, respectively). | Tolvaptan | arginine vasopressin | Homo sapiens |
| 3 | In tolvaptan-treated subjects with higher baseline copeptin levels, a larger treatment effect was noted with respect to kidney growth rate and eGFR decline. | Tolvaptan | arginine vasopressin | Homo sapiens |
| 4 | Tolvaptan-treated subjects with a larger percentage increase in copeptin from baseline to week 3 had a better disease outcome, with less kidney growth and eGFR decline after three years. | Tolvaptan | arginine vasopressin | Homo sapiens |