Title : MicroRNA‑1 downregulation induced by carvedilol protects cardiomyocytes against apoptosis by targeting heat shock protein 60.

Pub. Date : 2019 May

PMID : 30896796






2 Functional Relationships(s)
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1 The expression of heat shock protein 60 (HSP60), a direct target of miR-1, was identified to be decreased in MI and H2O2-induced apoptosis, which was associated with a decrease in Bcl-2 and an increase in Bax; expression was restored following treatment with carvedilol. Hydrogen Peroxide heat shock protein family D (Hsp60) member 1 Rattus norvegicus
2 The expression of heat shock protein 60 (HSP60), a direct target of miR-1, was identified to be decreased in MI and H2O2-induced apoptosis, which was associated with a decrease in Bcl-2 and an increase in Bax; expression was restored following treatment with carvedilol. Hydrogen Peroxide heat shock protein family D (Hsp60) member 1 Rattus norvegicus