Pub. Date : 2019 Mar 19
PMID : 30890751
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These various outcomes could also be attenuated by silencing of glutathione S-transferase P1 (GSTP1), a mediator of metabolic alterations and drug resistance in various cancers, and a regulator of cysteine oxidation. | Cysteine | glutathione S-transferase pi 1 | Homo sapiens |
| 2 | These various outcomes could also be attenuated by silencing of glutathione S-transferase P1 (GSTP1), a mediator of metabolic alterations and drug resistance in various cancers, and a regulator of cysteine oxidation. | Cysteine | glutathione S-transferase pi 1 | Homo sapiens |
| 3 | Collectively, our findings indicate DUOX1 deficiency in lung cancers promotes dysregulated EGFR signaling and enhanced GSTP1-mediated turnover of EGFR cysteine oxidation, which result in enhanced nuclear EGFR localization and tumorigenic properties. | Cysteine | glutathione S-transferase pi 1 | Homo sapiens |