Title : Plant-Derived Polyphenols Modulate Human Dendritic Cell Metabolism and Immune Function via AMPK-Dependent Induction of Heme Oxygenase-1.

Pub. Date : 2019

PMID : 30881359






2 Functional Relationships(s)
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1 Moreover, pharmacological inhibition of AMPK was found to reverse the observed reduction of DC maturation by carnosol and curcumin. Curcumin protein kinase AMP-activated non-catalytic subunit beta 1 Homo sapiens
2 This study therefore describes a novel relationship between metabolic signaling via AMPK and HO-1 induction by carnosol and curcumin in human DC, and characterizes the effects of these polyphenols on DC immunometabolism for the first time. Curcumin protein kinase AMP-activated non-catalytic subunit beta 1 Homo sapiens