Title : Cardioprotective effects of constitutively active MEK1 against H2O2-induced apoptosis and autophagy in cardiomyocytes via the ERK1/2 signaling pathway.

Pub. Date : 2019 Apr 23

PMID : 30876692






1 Functional Relationships(s)
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1 As a result, CaMEK attenuated H2O2-induced apoptosis and cytotoxicity in NCMs, evidenced by decreased apoptotic cells and the ratio of Bax/Bcl-2, increased the mitochondrial membrane potential (Deltapsim) and cell vitality and reduced the level of lactate dehydrogenase (LDH). Hydrogen Peroxide BCL2, apoptosis regulator Rattus norvegicus