Title : A cytosine modification mechanism revealed by the structure of a ternary complex of deoxycytidylate hydroxymethylase from bacteriophage T4 with its cofactor and substrate.

Pub. Date : 2019 Mar 1

PMID : 30867918






1 Functional Relationships(s)
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1 In contrast to the extensively studied TS, the hydroxymethylation mechanism of a cytosine base is not well understood due to the lack of a ternary complex structure of dCH in the presence of both its substrate and cofactor. Cytosine dch Drosophila melanogaster