Title : Systematic analysis and identification of unexpected interactions from the neuroprotein drug interactome in hydrocephalus pharmacological intervention.

Pub. Date : 2019 Feb

PMID : 30866733






1 Functional Relationships(s)
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1 It is found that the Furosemide and Triamterene have significant cytotoxic effects on normal human astrocytes, in which the Triamterene can inhibit the neurokinase ROCK2, a representative of putative unexpected targets, with a high activity, which is comparable with the sophisticated ROCK2 inhibitor Fasudil. fasudil Rho associated coiled-coil containing protein kinase 2 Homo sapiens