Title : Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer.

Pub. Date : 2019 Jun

PMID : 30862724






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Y391 phosphorylation occurs in both monomeric and dimeric IDH1, which enhances cofactor (NADP+ or NADPH) binding. NADP isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens
2 Y391 phosphorylation occurs in both monomeric and dimeric IDH1, which enhances cofactor (NADP+ or NADPH) binding. NADP isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens