Title : Erastin decreases radioresistance of NSCLC cells partially by inducing GPX4-mediated ferroptosis.

Pub. Date : 2019 Mar

PMID : 30854078






2 Functional Relationships(s)
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1 Erastin-induced and GPX4-inhibition-induced cell death could partially be rescued by deferoxamine, but not Z-VAD-FMK and olaparib, which indicated that erastin and GPX4-inhibition induced ferroptosis in the radioresistant cells. Deferoxamine glutathione peroxidase 4 Homo sapiens
2 Erastin-induced and GPX4-inhibition-induced cell death could partially be rescued by deferoxamine, but not Z-VAD-FMK and olaparib, which indicated that erastin and GPX4-inhibition induced ferroptosis in the radioresistant cells. Deferoxamine glutathione peroxidase 4 Homo sapiens