Title : Asprosin impairs insulin secretion in response to glucose and viability through TLR4/JNK-mediated inflammation.

Pub. Date : 2019 Apr 15

PMID : 30853600






1 Functional Relationships(s)
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1 Treatment of MIN6 cells and human primary islets with palmitate increased phosphorylation of the inflammatory marker nuclear factor-kappa B (NFkappaB) and the release of pro-inflammatory cytokines including TNF and MCP-1 and decreased glucose-stimulated insulin secretion and cell viability. Palmitates insulin Homo sapiens