Pub. Date : 2019 Jun
PMID : 30853336
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: Aggregation of tau into paired helical filament (PHF) is a hallmark of Alzheimer"s disease (AD), and Cys-mediated disulfide bond formation plays a vital role in tau fibrillation. | Cysteine | microtubule associated protein tau | Homo sapiens |
| 2 | BACKGROUND: Aggregation of tau into paired helical filament (PHF) is a hallmark of Alzheimer"s disease (AD), and Cys-mediated disulfide bond formation plays a vital role in tau fibrillation. | Cysteine | microtubule associated protein tau | Homo sapiens |
| 3 | While intermolecular disulfide bond between Cys residues in microtubule-binding repeat (MTBR) region facilitates tau aggregation, intramolecular disulfide bond attenuates the same, though the molecular basis for such phenomenon remains obscure. | Cysteine | microtubule associated protein tau | Homo sapiens |