Title : Study on the interaction and antioxidant activity of theophylline and theobromine with SOD by spectra and calculation.

Pub. Date : 2019 May 15

PMID : 30852283






5 Functional Relationships(s)
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1 Study on the interaction and antioxidant activity of theophylline and theobromine with SOD by spectra and calculation. Theobromine superoxide dismutase 1 Homo sapiens
2 The antioxidation of TP and TB as well as the effect of the antioxidation and activity of copper-zinc superoxide dismutase (SOD) with TP and TB were investigated. Theobromine superoxide dismutase 1 Homo sapiens
3 The contents of MDA in cells showed that both TP (14.49 mumol/g) and TB (14.25 mumol/g) are active in oxidation resistance and closed to the antioxidant effect of SOD (13.77 mumol/g). Theobromine superoxide dismutase 1 Homo sapiens
4 The interactions between TP/TB and SOD were studied by ultraviolet spectrum, fluorescence spectrum and molecular docking. Theobromine superoxide dismutase 1 Homo sapiens
5 The results showed that the complex of TP/TB and SOD with 1:1 component was stabilized by hydrogen bonding and van der Waals forces. Theobromine superoxide dismutase 1 Homo sapiens