Title : Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease.

Pub. Date : 2019 Apr 15

PMID : 30851693






1 Functional Relationships(s)
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1 For all the tacrine-tryptophan heterodimers, favorable inhibitory effect on hAChE as well as on hBChE was coined to the optimal spacer length ranging from five to eight carbon atoms between these two pharmacophores. Carbon acetylcholinesterase (Cartwright blood group) Homo sapiens