Title : Defining the Role of Nucleotide Flipping in Enzyme Specificity Using 19F NMR.

Pub. Date : 2019 Mar 27

PMID : 30841696






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Countering this threat are three types of glycosylases that excise thymine from G T mispairs, including thymine DNA glycosylase (TDG). Thymine thymine DNA glycosylase Homo sapiens
2 Countering this threat are three types of glycosylases that excise thymine from G T mispairs, including thymine DNA glycosylase (TDG). Thymine thymine DNA glycosylase Homo sapiens
3 TDG preferentially removes thymine from DNA contexts in which cytosine methylation is prevalent, including CG and one non-CG site. Thymine thymine DNA glycosylase Homo sapiens
4 A linear free energy correlation reveals that TDG attains context specificity for thymine excision through modulation of nucleotide flipping. Thymine thymine DNA glycosylase Homo sapiens