Pub. Date : 2019 Feb
PMID : 30839497
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Halofuginone protects HUVECs from H2O2-induced injury by modulating VEGF/JNK signaling pathway. | halofuginone | vascular endothelial growth factor A | Homo sapiens |
| 2 | Finally, it was shown that halofuginone upregulated VEGF expressions, which functioned by inhibiting sustained JNK activation, thus protecting HUVECs. | halofuginone | vascular endothelial growth factor A | Homo sapiens |
| 3 | CONCLUSION: Halofuginone has powerful effects in protecting HUVECs from H2O2-induced apoptosis, via upregulating VEGF and inhibiting overactivated JNK phosphorylation. | halofuginone | vascular endothelial growth factor A | Homo sapiens |