Pub. Date : 2019 May 1
PMID : 30836163
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that nicotine simultaneously activates AKT/mTOR pathway in HPV-immortalized cervical epithelial (H8) cell line, followed by elevation of 4EBP1/eIF4E axis expression and its translational activity with dose-dependent and time-dependent manners. | Nicotine | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Taken together, it can be concluded that nicotine promotes H8 cell proliferation by activating AKT/mTOR pathway, as well as 4EBP1/eIF4E axis and its translational activity. | Nicotine | AKT serine/threonine kinase 1 | Homo sapiens |