Pub. Date : 2019 Jun
PMID : 30827017
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Acarbose suppressed LPS-induced acetylation of histones H3 (H3) and H4 in the IP-10 and MCP-1 promoter regions. | Acarbose | C-C motif chemokine ligand 2 | Homo sapiens |
| 2 | These findings revealed the suppressive effects of acarbose on IP-10, MCP-1, MDC, and TNF-alpha production in THP-1 cells via, at least partially, the p38, JNK, ERK, and NF-kappaB-p65 pathways, as well as through epigenetic regulation via histone H3 and H4 acetylation. | Acarbose | C-C motif chemokine ligand 2 | Homo sapiens |