Title : Regulation of macrophage eicosanoid production by hydroperoxy-and hydroxy-eicosatetraenoic acids.

Pub. Date : 1986 Jan 1

PMID : 3082323






1 Functional Relationships(s)
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1 Resident mouse peritoneal macrophages when exposed to zymosan during the first day of cell culture synthesize and secrete large amounts of prostaglandin E2 (PGE2) and leukotriene C4 (LTC4), the respective products of cyclo-oxygenase- and 5-lipoxygenase-catalysed oxygenations of arachidonic acid. Leukotriene C4 arachidonate 5-lipoxygenase Mus musculus